About Stem Hospital

Stem Hospital: A Global Pioneer in Integrated Regenerative Medicine

Stem Hospital is a world-class integrative healthcare institution combining Traditional Chinese Medicine (TCM), Modern Western Medicine, and Cutting-Edge Biotechnology into a “Trinity Model”. This model supports personalized, full-lifecycle health management rooted in both ancient wisdom and modern science.

We deliver internationally standardized care supported by:

• A globally renowned team of clinical and research experts

• A robust pipeline of patented technologies and proprietary therapies

• An international telemedicine network

• Global translational medicine hubs across the U.S., Japan, Germany, Switzerland, and Australia

Three Core Platforms for Human Longevity & Regeneration

1. Biological R&D Platform

A state-of-the-art biotechnology hub with over 4,000m² of GMP-certified cleanrooms, including:

• Cell Manufacturing Center

• CAR-T Engineering Lab (Next-Gen Solid Tumor CAR-T Cell Design)

• Gene Editing and Precision Immunotherapy Unit

Recognitions & Capacity:

• Provincial Postdoctoral & Graduate Innovation Workstations

• Holder of multiple PCT international patents

• Proprietary multi-target CAR-T designs with proven efficacy in solid tumors

• Mastery of cutting-edge techniques: CRISPR-based editing, T-cell electroporation, targeted knock-in/knock-out, cell cryopreservation at -196°C

Performance Benchmarks:

• MSC culture time reduced from 5–7 days to 6–8 hours

• Immune cell culture yield up to 15+ billion cells per batch

• Clinically viable expanded MSCs, NK, DC, and Tregs with enhanced activity and viability

2. Precision Rehabilitation Platform

A holistic system implementing MDT (Multidisciplinary Team)-based rehabilitation through:

• Clinical Experience Center

• Therapeutic Hot Spring Recovery Center

• Intangible TCM Heritage & Treatment Center

• Integrated Oncology Recovery Center

• Regenerative Medicine & Cell Therapy Translational Center

This platform bridges evidence-based Western rehabilitation with individualized TCM wellness, promoting recovery after surgery, cancer therapy, chronic illnesses, and neurodegenerative conditions.

3. Smart Prevention Platform

Designed to shift healthcare from reactive to proactive, the platform includes:

• Functional Diagnostics Hub (clinical bloodwork, genomics, proteomics, metabolomics)

• Skin Regeneration & Anti-Aging Unit

• Chronic Disease Co-Management Center

• “Preventive TCM” Early Intervention Sub-center

• Hormonal & Intimate Health Sub-center

Core Technologies: Mesenchymal Stem Cells (MSCs) and Immune Cells

Mesenchymal Stem Cells (MSCs)

MSCs are multipotent stromal cells with the ability to differentiate into a variety of cell types and regulate immune responses.

Sources: Umbilical cord, placenta, bone marrow, adipose tissue, amniotic membrane, dental pulp
Advantages:

• Low immunogenicity, high safety

• No need for HLA matching

• High proliferation potential

• Wide clinical applicability

• Stable genome, non-tumorigenic

Therapeutic Functions:

• Immunomodulation: Inhibit T-cell overactivation and restore immune tolerance

• Tissue Regeneration: Osteoblasts, chondrocytes, adipocytes, muscle, connective tissue

• Homing Effect: Navigate to inflammation/injury sites via cytokine gradient sensing

• Anti-fibrosis: In liver, lung, and myocardial conditions

• Anti-apoptotic Effects: Support survival of stressed or aging cells

Stem Cell Clinical Applications: Indications & Research Focus

Stem Hospital’s translational programs focus on the following medical domains:

Autoimmune & Inflammatory Diseases

• Rheumatoid arthritis

• Systemic lupus erythematosus (SLE)

• Crohn’s disease

• Ulcerative colitis

• Psoriasis

Neurological & Neurodegenerative Disorders

• Parkinson’s disease

• Alzheimer’s disease

• Spinal cord injury

• Stroke recovery

• Multiple sclerosis

Orthopedic & Musculoskeletal Conditions

• Osteoarthritis

• Intervertebral disc degeneration

• Avascular necrosis

• Cartilage injury

Cardiovascular & Pulmonary Disorders

• Myocardial infarction recovery

• Dilated cardiomyopathy

• Pulmonary fibrosis

• COPD

Metabolic & Endocrine Conditions

• Type 1 & Type 2 Diabetes

• Diabetic foot ulcers

• Obesity-related inflammation

Oncology Supportive Care

• MSCs as immunomodulators during chemotherapy

• CAR-T for solid tumors

• NK cells for minimal residual disease control

Aesthetic & Regenerative Therapies

• Anti-aging (skin rejuvenation, telomere repair)

• Hair regeneration

• Intimate rejuvenation

• Facial volume restoration

Immune Cells: The Body's Elite Defense System

From age 20, the thymus declines by 15% annually, becoming inactive by age 40. Bone marrow fat infiltration and calcification after age 50 drastically reduce immune cell production.

To reverse this decline, Stem Hospital offers immune cell banking—harvesting and cryopreserving NK cells, γδ T-cells, DC cells, and Tregs for future autologous or allogeneic applications. These cells can be reactivated during periods of disease, aging, or high risk.

Global Collaboration & Vision

Led by:

• Academician Xu (Chief Scientist, CAS)

• Prof. Yin (Ph.D. supervisor, China Pharmaceutical University)

• Prof. Jin (Postdoc, U.S. National Medical Center)

Stem Hospital owns over 100 PCT patents and is building a global ecosystem of biotech translation, regenerative medicine, and digital health innovation.